Luos engine needs to acces your hardware to properly work.
When creating a Luos network, if you have a product with several nodes, it is mandatory to configure your MCU to create the network's physical layer. In Luos's examples on GitHub, we use the Robus network interface with RS485 or one-wire communication (for this physical layer see Electronic design page), but other networks can be used as well.
Board examples and driver sources are available on GitHub. We encourage you to use them as a reference, the way you want.
You can find the schematics of a Luos-ready board called L0 on Github for a quick hardware example.